You can apply a user profile at any time. The defaults; preferences, and options contained within the profile will overwrite the existing values for those defaults, preferences and options, while leaving all others unchanged. Note that while general PowerDesigner options take effect immediately, model options and display preferences only take effect when you create a new model.
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Select to open the Apply User Profile dialog:
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[optional] Click the Change User Profile Directory button, and browse to a folder where you have saved user profiles. By default they are saved in the install_dir/Resource Files/User Profiles directory.
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Select a profile from the list and click OK.
The user profile is applied, and overwrites the defaults, preferences, and options contained within it with the values it defines.